It is not surprising that you are tired. you stayed up until 12 last night.A. InsteadB.

问题补充：

It is not surprising that you are tired. , you stayed up until 12 last night.

A. Instead

B. In fact

C. After all

D. What’s more

答案：

A. Instead

B. In fact

(答案→)C. After all

D. What’s more

解析：本题的含义是你困倦了并不令人感到诧异，毕竟昨天晚上你熬夜熬到12点，after all表示毕竟的意思，故本题选C。