there are many differences in personality they have a lot common.A. While; inB. Although;

问题补充：

there are many differences in personality, they have a lot common.

A. While; in

B. Although; on

C. In spite of; in

D. Thanks to; on

答案：

(答案→)A. While; in

B. Although; on

C. In spite of; in

D. Thanks to; on

解析：本题易误选C。in spite of 为介词短语，后接名词、代词或短语，不能接句子，而本句第一个空后是句子形式，需填连词， while用作连词，其中一层意思为“虽然；尽管”; have…in common为固定短语，意思为“有共同之处”。