抗CD3单克隆抗体,anti-CD3 monoclonal antibody
1)anti-CD3 monoclonal antibody抗CD3单克隆抗体
1.At present,anti-CD3 monoclonal antibody has been widely used in Graft rejection reaction after organ transplant in clinic treatment, which has significant therapeutic effects.目前,抗CD3单克隆抗体已广泛应用于临床治疗器官移植后排斥反应,疗效显著,但机体易产生特异性免疫反应,导致鼠源性抗CD3单克隆抗体被快速清除,半衰期明显缩短,从而限制了其治疗作用。
英文短句/例句
1.Reversal of New-onset Autoimmune Diabetes by a Short-time and Low-dose Treatment with Anti-CD3 Monoclonal Antibodies;抗CD3单克隆抗体治疗Ⅰ型糖尿病及机制的研究
2.Apoptosis and autophagy induced by anti-CD3 monoclonal antibody in human peripheral blood CD4~+CD25~+T lymphocytes抗CD3单克隆抗体对人CD4~+CD25~+T淋巴细胞凋亡和自噬的影响
3.Study on Modification of Monoclonal Antibody Anti-CD3 with mPEG;PEG修饰鼠抗人CD3单克隆抗体的研究
4.Development and Characterization of Monoclonal Antibodies Against Chicken CD3 and IL-2;鸡CD3和IL-2分子单克隆抗体的研制与鉴定
5.Amplification, Cloning and Sequence Analysis of the Genes of V_H and V_K of an Anti-human CD3 Monoclonal Antibody;抗人CD3单抗重、轻链可变区基因的体外扩增、克隆和序列分析
6.Optimization of Serum-free Culture System for CHO Cell with Stable Production of Anti-CD3 Humanized Antibody;抗CD3单克降抗体分泌细胞体外培养条件的优化
7.Cloning and Expression of Anti-CD3 Human/Murine Chimeric Antibody in Pichia Pastoris;抗CD3人鼠嵌合抗体的克隆及其在毕赤酵母中的表达
8.Molecular Directed Evolution of Reshaped Anti-CD3 Single Chain Fv Fragment;抗CD3改型单链抗体的分子定向进化
9.myosin mono clonal antibody肌浆球蛋白单克隆抗体
10.Study of the Optimum Pairing of Polyclonal Antibodies and Monoclonal Antibodies with Sandwich ELISA单克隆抗体与多克隆抗体配对ELISA方法比较
11.Preparation and Identification of Monoclonal Antibodies and Anti-Idiotype Antibodies Against Aeromonas Caviae;豚鼠气单胞菌单克隆抗体及抗独特型单克隆抗体的制备研究
12.The Preparation and Study on Anti-human-gastrin McAb and ScFv;抗人胃泌素单克隆抗体及其单链抗体的研制
13.Preparation of monoclonal antibodies against the MSP5 of Anaplasma marginale抗牛边缘无浆体MSP5单克隆抗体的制备
14.Preparation and identification of a monoclonal antibody against FLT3 receptor抗FLT3受体单克隆抗体的制备与鉴定
15.Preparation and identification of anti-EPF monoclonal antibodies抗早孕因子单克隆抗体的制备与鉴定
16.Anti-hBLyS Polyclonal, Monoclonal Antibody Preparation and Application;抗hBLyS多、单克隆抗体的研制及应用
17.Identification and Application of the Monoclonal Antibodies Against SARS-CoV;抗SARS-CoV单克隆抗体的鉴定及应用研究
18.Research on Development of Monoclonal Antibody Against Chicken IgM and Its Application;抗鸡IgM单克隆抗体的制备及应用研究
相关短句/例句
CD3 mAbCD3单克隆抗体
1.Total cytoplastic mRNA of PBMC stimulated by anti-CD3 mAb at continuous time points was isolated and reversed to cDNA.目的建立细胞因子mRNA实时定量PCR的检测方法,并探讨人单个核细胞(PBMC)在激发型CD3单克隆抗体作用下,细胞因子mRNA的表达。
3)murine anti-human CD3 mAb抗人CD3小鼠单克隆抗体
4)anti-CD3 monoclonal antibody activated killer cell(CD3AK)抗CD3单克隆抗体激活的杀伤细胞(CD3AK细胞)
5)monoclonal antibody单克隆抗体
1.Preparation and identification ofmonoclonal antibody against ginsenoside Rb1;人参皂苷Rb1单克隆抗体的制备与鉴定
2.Development ofmonoclonal antibody against Fumonisin B_1 and ELISA-kit of quantitative analysis for Fumonisin B_1;抗伏马菌素B_1单克隆抗体的制备及试剂盒的研制
3.Determination of fipronil in water by ELISA based onmonoclonal antibody;单克隆抗体间接竞争ELISA测定水体中氟虫腈
6)monoclonal antibodies单克隆抗体
1.Production and identification ofmonoclonal antibodies to chCD25;抗鸡CD25单克隆抗体的制备与鉴定
2.Production and identification ofmonoclonal antibodies against proteinase activated receptor-1;蛋白酶活化受体-1单克隆抗体的制备与鉴定
3.Expression and purification of recombinant nucleocapsid protein of SARS Coronavirus and preparation of itsmonoclonal antibodies;重组SARS-CoV核衣壳蛋白的表达纯化及其单克隆抗体的制备鉴定
延伸阅读
单克隆抗体单克隆抗体monoclonalantibody单一克隆产生的并针对单一抗原决定簇的均一性抗体。它见于免疫增生性疾病，也可通过杂交瘤技术人工产生。细胞杂交是20世纪60年代建立起来的一种新技术，把种内或种间细胞融合后，可成为新的细胞。这种含有双亲细胞核的细胞经有丝分裂为两个单核子细胞，子细胞核内含有双亲细胞的染色体。1975年分子生物学家G.J.F.克勒和C.米尔斯坦在细胞杂交技术的基础上，创立杂交瘤技术，他们把可在体外培养和大量增殖的小鼠骨髓瘤细胞与经抗原免疫后的纯系小鼠脾细胞融合，成为杂交细胞系，既具有瘤细胞易于在体外无限增殖的特性，又具有抗体形成细胞的合成和分泌特异性抗体的特点。将这种杂交瘤作单个细胞培养，可形成单细胞系，即单克隆。利用培养或小鼠腹腔接种的方法，便能得到大量的、高滴度的、非常均一的抗体，其结构、氨基酸顺序、特异性等都是一致的，而且在培养过程中，只要没有变异，不同时间所分泌的抗体都能保持同样的结构与机能。这种单克隆抗体是用其他方法所不能得到的。这项新技术从根本上解决了在抗体制备中长期存在的特异性和可重复性问题。单克隆抗体可直接用于人类疾病的诊断、预防、治疗以及免疫机制的研究，为人类恶性肿瘤的免疫诊断与免疫治疗开辟了广阔前景。
