单倍体相合骨髓移植,haploidentical bone marrow transplantation
1)haploidentical bone marrow transplantation单倍体相合骨髓移植
1.To explore the occurrence patterns of neurological complications followinghaploidentical bone marrow transplantation, a series of clinical data as the onset time, etiology, choices of therapies and prognosis in 10 patients with neurological disorders were summarized.结果表明:74例接受单倍体相合骨髓移植病人中10例发生并发症,其中3例病人出现脑出血,感染3例(真菌感染,CMV脑炎,单纯疱疹病毒性脑炎各1例),癫痫、格林-巴利综合征、脑病和精神分裂症各1例,因神经系统并发症直接导致死亡的患者4例。
2.To explore the occurrence patterns of pulmonary complications at different stages inhaploidentical bone marrow transplantation, a series of clinical data as the onset time, etiology, management choices and prognosis in 18 patients with pulmonary disorders were summarized.为了探讨单倍体相合骨髓移植术后不同时期肺部并发症发生情况 ,对 18例单倍体相合骨髓移植术后肺部并发症的发生时间、病因、治疗措施及预后等临床资料进行了总结分析。
3.This study was purpused to analyze the characteristics of T cell receptor repertoire in target organs of murine graft-versus-host afterhaploidentical bone marrow transplantation(hiBMT) and the molecular characteristics of complementarity determining region3 (CDR3) repertoires of monoclonal T cell in liver, skin and ileum in murine after hiBMT.本课题通过单倍体相合骨髓移植小鼠模型,研究GVHD靶器官的器官特异性T细胞受体谱型特点,以及GVHD靶器官克隆性T细胞的TCRBVCDR3分子特征。
英文短句/例句
1.Effectiveness of Allogeneic NK Cells in Haploidentical Bone Marrow Transplantation for Leukemic Mice异基因NK细胞在白血病小鼠单倍体相合骨髓移植中的作用(英文)
an-specific T Cell Receptor Repertoire in Target Organs of Murine Graft-versus-Host Disease after Haploidentical Bone Marrow Transplantation单倍体相合骨髓移植小鼠GVHD靶器官的器官特异性T细胞受体克隆谱型的分子特征
3.Haploidentical Allogeneic Bone Marrow Stem Cell Transplantation Combined with Peripheral Blood Stem Cells for Therapy of Leukemia骨髓联合外周血单倍体相合造血干细胞移植治疗白血病
4.Clinical exploration on treatment of acute mixed lineage leukemia with HLA-haploidentical blood and bone marrow stem cellsHLA单倍体外周血联合骨髓干细胞移植治疗急性混合细胞白血病的临床观察
5.A Study of Haploidentical Mesenchymal Stem Cells and Hematopoietic Stem Cell Co-transplantation with Nonmyeloablative Conditioning in Rhesus Model猕猴间充质干细胞联合非清髓单倍体造血干细胞移植的实验研究
6.Simple bone cysts in teenagers treated by grafting of bioactive glass and autologous bone marrow生物活性玻璃复合自体骨髓移植治疗青少年单纯性骨囊肿
7.Study on Haploidentical Transplantation for Treatment of Murine Solid Hepatoma 22;单倍体相合细胞移植治疗小鼠H22实体瘤的实验研究
8.Clinical Study of Haploidentical Peripheral Blood Stem Cell Transplantation without Ex Vivo T-cell Depletion for High-risk Hematological Malignancies单倍体相合外周血造血干细胞移植治疗恶性血液病
9.Deep fascia composite autologous red bone marrow transplantation for the treatment of fracture nonunion自体深筋膜复合自体红骨髓移植治疗骨不连
10.Clinical observation on percutaneous autologous bone marrow grafting for treatment of fracture nonunion经皮自体骨髓移植治疗骨折不愈合的临床观察
11.Study of Monoclonal Antibody Used in Preparative Regimen before Bone Marrow Transplantation单克隆抗体应用于骨髓移植预处理的实验研究
12.Implantation of autologous bone marrow mononuclear cells for treatment of ischemia hindlimb in rats自体骨髓单个核细胞移植治疗大鼠后肢缺血
13.Treatment of lower limb tubular bone defect with auto fibula intra-bone marrow transplantation and mix impaction bone graft自体腓骨髓腔内移植并混合打压植骨治疗下肢管状骨缺损
14.Role of Donor-derived Natural Killer Cell in MHC Haplotype-mismatched Bone Marrow Transplantation in Mice;供者NK细胞在小鼠MHC半相合骨髓移植的作用
15.The bone marrow of the chimerism mice was grafted into the host mice.最后将该嵌合体小鼠的骨髓移植到宿主体内。
16.Experimental Study of bone marrow mobillization combined with Autologous stem cell transplantation in Rabbits on chronic lower extremity ischemia兔自体骨髓干细胞移植联合骨髓动员治疗下肢缺血的实验研究
17.A Study on Chemical Modification of Doner H-2 Antigen in Haploidentical BMT in a Murine Model;mPEG修饰移植物后行小鼠半相合骨髓移植的实验研究
18.Investigation on Osteodifferentiation of MSCs Induced by Osteoblast Transplanted into Bioceramic Scaffolds in Vivo;成骨细胞诱导骨髓基质细胞后结合陶瓷复合物体内移植成骨观察
相关短句/例句
haploidentical bone marrow transplantation单倍相合骨髓移植
1.This study was aimed to investigate the therapeutic effect of growth factor-primed donor peripheral mononuclear stem cell infusion (DMNCI) for patients with relapsed leukemia afterhaploidentical bone marrow transplantation (BMT).本研究探讨同一供者外周血单个核细胞输注(DMNCI)治疗单倍相合骨髓移植后白血病复发的疗效和安全性。
2.The purpose of study was to investigate the impact of killer immunoglobulin-like receptor (KIR) and its ligand onhaploidentical bone marrow transplantation.分析了74例KIR基因及其配体分子HLA-Cw的分布频率和特点,同时比较KIR分子配体缺失与否对单倍相合骨髓移植患者总体生存、无病生存、GVHD发生以及复发等的影响。
3)non-T cell depleted haploidentical BMT单倍相合未去T细胞骨髓移植
4)Haploidentical bone marrow transplantation单倍型骨髓移植
1.Establishment of murine haploidentical bone marrow transplantation model and detection of T cell receptor clonal in target organs of graft-versus-host disease单倍型骨髓移植小鼠移植物抗宿主病模型的建立及移植物抗宿主病靶器官T细胞受体克隆检测
5)haploidentical transplantation单倍体相合移植
6)haploidentical hematopoietic stem cell transplantation单倍体相合造血干细胞移植
1.The aim of this study was to evaluate the impact of donor killer cell immunoglobulin-like receptor(KIR)and recipient HLA genotypes on outcome followinghaploidentical hematopoietic stem cell transplantation(HSCT).本研究探讨供者杀伤细胞免疫球蛋白样受体(KIR)和受者人类白细胞抗原(HLA)基因型在单倍体相合造血干细胞移植(HSCT)预后中的意义。
2.To investigate the characteristics and significance of reconstitution of peripheral blood plasmacytoid dendritic cell (PDC) precursors after allogeneic human leukocyte antigen mismatched/haploidentical hematopoietic stem cell transplantation, and its relationship with chronic graft versus host disease(cGVHD)and relapse, 19 patients with leukemia were enrolled for this study.为了探讨浆样树突状细胞(PDC)在单倍体相合造血干细胞移植术后重建的特点及其与慢性移植物抗宿主病(cGVHD)和患者复发的关系,采用流式细胞术对19例白血病患者移植后外周血树突状细胞(DC)亚群晚期重建进行动态监测,并将其与患者cGVHD和复发的关系进行分析。
延伸阅读
骨髓移植骨髓移植bonemarrowtransplantation将正常骨髓由静脉输入患者体内，以取代病变骨髓的治疗方法。简称BMT。骨髓中有大量多能造血干细胞，具有自我复制和分化两种基本功能，在患者体内植活后，患者的造血功能和免疫功能即得以重建。类型根据骨髓的来源不同，BMT有3种类型：①同种异基因BMT。指人类不同个体间的移植，目前大多数BMT都指此而言，供者和受者的人类白细胞抗原(HLA）配型相合是移植成功的必要条件，亲兄弟姐妹间相合的机率是25％，无关供者相匹配的机率很少。②同基因BMT。即同卵双生子女间的BMT，效果最好。③自体BMT。即用自身的骨髓，不需供髓者，此法简便，易于推广，可广泛用于独生子女。适应症受者的年龄一般应小于45岁，自体BMA可高至55岁，应无重大内、外科疾病，具体适用于如下两类疾病，第一类是恶性疾病，包括：①完全缓解后的急性白血病，BMT后的5年生存率可达70％。②慢性粒细胞白血病的慢性期，80％可长期缓解或根治。③其他如难治性恶性淋巴瘤、多发性骨髓瘤、小细胞肺癌等常采用自体BMT，疗效显著。第二类是非恶性疾病如再生障碍性贫血和重症联合免疫缺陷病等。今后随着供髓者的选择、感染和移植物抗宿主病防治的解决，BMT必将被推广和显示巨大生命力。
