单克隆抗体药物,monoclonal antibody therapeutics
1)monoclonal antibody therapeutics单克隆抗体药物
1.Advance onmonoclonal antibody therapeutics for tumor;抗肿瘤单克隆抗体药物的研究进展
2)anti-drug monoclonal antibodies药物单克隆抗体
1.The methods and principles for the preparation of drug-protein conjugates as immunogen and the main points of producinganti-drug monoclonal antibodies with B-lymphoblasts hybridoma technique are introduced briefly in this paper.概述了药物(含激素类药物)半抗原合成人工免疫原方法以及采用B-淋巴细胞杂交瘤技术制备药物单克隆抗体的要点,着重介绍了药物单克隆抗体作为几种免疫分析方法的核心试剂,在临床药理学研究及生物样品的药物残留分析中的应用,并对其进行了评述,以期了解药物单克隆抗体的应用现况及前景。
英文短句/例句
1.Establishment of Hybridoma Cell Lines Secreting Monoclonal Antibodies Against Sulfonamides分泌抗磺胺类药物单克隆抗体杂交瘤株的建立
2.Development and Preliminary Application of the Monoclonal Antibody Against Sulfonamides with Five-membered Heterocycle;含五元杂环磺胺类药物单克隆抗体的制备及初步应用
3.Characterization of Morphine-carrier Protein Conjugate and Pharmacological Evaluation of Anti-morphine Monoclonal Antibody;吗啡—载体蛋白交联物的鉴定及抗吗啡单克隆抗体的药理学评价
4.Detection of Drug Resistance of Staphylococcus Aureus from Animals and Expression of SEA Gene and Preparation of Monoclonal Antibodies against SEA动物源金黄色葡萄球菌耐药性检测及其肠毒素A基因的克隆表达及单克隆抗体的制备
5.Preparation of the Monoclonal Antibody Against Advanced Glycation End Products;晚期糖基化终产物单克隆抗体的制备
6.Application of Monoclonal Antibody Technology on Plant单克隆抗体技术在植物中的研究应用
7.Preparation and Characterization of Monoclonal Antibody Against CP4-EPSPS;抗CP4-EPSPS单克隆抗体的制备和生物学特性的研究
8.Preparation and Application of Biotinylated Anti-AIB1 Moniclonal Antibody生物素化抗AIB1单克隆抗体的制备及应用研究
9.myosin mono clonal antibody肌浆球蛋白单克隆抗体
10.Analysis of Biological Functions of Mouse Anti Human CD52 Monoclonal Antibody-HI186 and Construction of ScFv Based on HI186;小鼠抗人CD52单克隆抗体HI186的生物学功能研究及其单链抗体的构建
11.Biological Function Research of a Mouse Anti Human CD22 Monoclonal Antibody HIB22 and Development of Single Chain Fv Derived from HIB22 Hybridoma小鼠抗人CD22单克隆抗体HIB22的生物学功能研究及其单链抗体的构建
12.First biotechnology product approved by FDA to treat patients with cancer- a monoclonal antibody called rituximab, used to treat one type of lymphoma.FDA批准首个治疗癌症的生物技术药物-一种称为利妥昔的单克隆抗体治疗一种淋巴瘤.
13.Cloning and Expression of Bovine Interferon-Gamma cDNA and Development of Monoclonal Antibodies Against the Expressed Product;牛γ干扰素基因cDNA的克隆、表达及其表达产物单克隆抗体的研制
14.Pharmacokinetics of Recombinant Human Rabies Monoclonal Antibody;重组人源化抗狂犬病毒单克隆抗体的药代动力学研究
15.Development and Identification of Monoclonal Antibodies to Sulfadiazine and Sulfonamides;抗磺胺嘧啶及碘胺类药母核结构单克隆抗体的制备与鉴定
16.Study of the Optimum Pairing of Polyclonal Antibodies and Monoclonal Antibodies with Sandwich ELISA单克隆抗体与多克隆抗体配对ELISA方法比较
17.Endocytosis of the Antigastric Cancer Monoclonal Antibodies and Their Immunoconjugates;胃癌单克隆抗体及其免疫交联物的内化研究
18.Monoclonal Antibody Therapies in Leukemias;单克隆抗体生物靶向治疗白血病的研究进展
相关短句/例句
anti-drug monoclonal antibodies药物单克隆抗体
1.The methods and principles for the preparation of drug-protein conjugates as immunogen and the main points of producinganti-drug monoclonal antibodies with B-lymphoblasts hybridoma technique are introduced briefly in this paper.概述了药物(含激素类药物)半抗原合成人工免疫原方法以及采用B-淋巴细胞杂交瘤技术制备药物单克隆抗体的要点,着重介绍了药物单克隆抗体作为几种免疫分析方法的核心试剂,在临床药理学研究及生物样品的药物残留分析中的应用,并对其进行了评述,以期了解药物单克隆抗体的应用现况及前景。
3)monoclonal antibody单克隆抗体
1.Preparation and identification ofmonoclonal antibody against ginsenoside Rb1;人参皂苷Rb1单克隆抗体的制备与鉴定
2.Development ofmonoclonal antibody against Fumonisin B_1 and ELISA-kit of quantitative analysis for Fumonisin B_1;抗伏马菌素B_1单克隆抗体的制备及试剂盒的研制
3.Determination of fipronil in water by ELISA based onmonoclonal antibody;单克隆抗体间接竞争ELISA测定水体中氟虫腈
4)monoclonal antibodies单克隆抗体
1.Production and identification ofmonoclonal antibodies to chCD25;抗鸡CD25单克隆抗体的制备与鉴定
2.Production and identification ofmonoclonal antibodies against proteinase activated receptor-1;蛋白酶活化受体-1单克隆抗体的制备与鉴定
3.Expression and purification of recombinant nucleocapsid protein of SARS Coronavirus and preparation of itsmonoclonal antibodies;重组SARS-CoV核衣壳蛋白的表达纯化及其单克隆抗体的制备鉴定
5)mAb[m?b]单克隆抗体
1.Development and Characterization of MAb against Haemagglutinin of Highly Pathogenic H5 Avian Influenza Virus;高致病性H5亚型禽流行性感冒病毒血凝素单克隆抗体的制备与初步应用
2.Preparation and characterization of non-agglutinatingmAbs against membrane antigen on human erythrocytes;抗人红细胞膜抗原非凝集型单克隆抗体的研制及特性鉴定
3.Studies on the antithrombotic effects of anti-plateletmAb SZ-21 F(ab′)_2 fragment;抗血小板单克隆抗体片段的抗栓效应研究
6)McAb单克隆抗体
1.Observation to the stability of theMcAb against the interior antigen of influenza A virus;抗甲型流感病毒内部抗原单克隆抗体的稳定性观察
2.Preparation and Characterization ofMcAb against SARS-associated Coronavirus;抗SARS冠状病毒单克隆抗体的制备和鉴定
3.Establishment of Hybridoma Cell SecretingMcAb Against DNA and Characterization of The SecretedMcAb;抗DNA单克隆抗体杂交瘤细胞株的建立及其抗体的鉴定
延伸阅读
单克隆抗体单克隆抗体monoclonalantibody单一克隆产生的并针对单一抗原决定簇的均一性抗体。它见于免疫增生性疾病，也可通过杂交瘤技术人工产生。细胞杂交是20世纪60年代建立起来的一种新技术，把种内或种间细胞融合后，可成为新的细胞。这种含有双亲细胞核的细胞经有丝分裂为两个单核子细胞，子细胞核内含有双亲细胞的染色体。1975年分子生物学家G.J.F.克勒和C.米尔斯坦在细胞杂交技术的基础上，创立杂交瘤技术，他们把可在体外培养和大量增殖的小鼠骨髓瘤细胞与经抗原免疫后的纯系小鼠脾细胞融合，成为杂交细胞系，既具有瘤细胞易于在体外无限增殖的特性，又具有抗体形成细胞的合成和分泌特异性抗体的特点。将这种杂交瘤作单个细胞培养，可形成单细胞系，即单克隆。利用培养或小鼠腹腔接种的方法，便能得到大量的、高滴度的、非常均一的抗体，其结构、氨基酸顺序、特异性等都是一致的，而且在培养过程中，只要没有变异，不同时间所分泌的抗体都能保持同样的结构与机能。这种单克隆抗体是用其他方法所不能得到的。这项新技术从根本上解决了在抗体制备中长期存在的特异性和可重复性问题。单克隆抗体可直接用于人类疾病的诊断、预防、治疗以及免疫机制的研究，为人类恶性肿瘤的免疫诊断与免疫治疗开辟了广阔前景。
