Nature Reviews Nephrology
[IF:19.684]
Plant-based diets to manage the risks and complications of chronic kidney disease
通过植物性饮食管理慢性肾病的风险及并发症
10.1038/s41581-020-0297-2
06-11, Review
Abstract & Authors:
Abstract:
Traditional dietary recommendations for patients with chronic kidney disease (CKD) focus on the quantity of nutrients consumed. Without appropriate dietary counselling, these restrictions can result in a low intake of fruits and vegetables and a lack of diversity in the diet. Plant nutrients and plant-based diets could have beneficial effects in patients with CKD: increased fibre intake shifts the gut microbiota towards reduced production of uraemic toxins; plant fats, particularly olive oil, have anti-atherogenic effects; plant anions might mitigate metabolic acidosis and slow CKD progression; and as plant phosphorus has a lower bioavailability than animal phosphorus, plant-based diets might enable better control of hyperphosphataemia. Current evidence suggests that promoting the adoption of plant-based diets has few risks but potential benefits for the primary prevention of CKD, as well as for delaying progression in patients with CKD G3–5. These diets might also help to manage and prevent some of the symptoms and metabolic complications of CKD. We suggest that restriction of plant foods as a strategy to prevent hyperkalaemia or undernutrition should be individualized to avoid depriving patients with CKD of these potential beneficial effects of plant-based diets. However, research is needed to address knowledge gaps, particularly regarding the relevance and extent of diet-induced hyperkalaemia in patients undergoing dialysis.
First Authors:
Juan J Carrero
Correspondence Authors:
Juan J Carrero
All Authors:
Juan J Carrero,Ailema González-Ortiz,Carla M Avesani,Stephan J L Bakker,Vincenzo Bellizzi,Philippe Chauveau,Catherine M Clase,Adamasco Cupisti,Angeles Espinosa-Cuevas,Pablo Molina,Karine Moreau,Giorgina B Piccoli,Adrian Post,Siren Sezer,Denis Fouque
